HOAT in DMF(0.6M/L) 1-Hydroxy-7-azabenzotriazole in DMF(0.6M/L）

REF: A01034-1
N-Hydroxy-7-azabenzotriazole (HOAt) is supplied as a 0.6 mol/L solution in DMF and serves as a highly efficient peptide coupling reagent and additive. It can be used independently or in combination with various coupling agents. HOAt not only effectively suppresses racemization but also accelerates reaction rates, making it particularly suitable for synthesizing sterically hindered peptides. Additionally, reactions involving HOAt allow for visual monitoring of coupling completion due to the distinctive color of its anionic intermediate.