PyBOP Benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate

REF: A01055
1H-Benzotriazol-1-yloxytris(1-pyrrolidinyl)phosphine hexafluorophosphate (PyBOP) is a new type of phosphorus-positive peptide condensation reagent, which avoids the production of carcinogenic byproducts of hexamethylphosphoramidonium produced by the traditional condensation agent BOP and promotes the coupling of carboxylic acids and amino acids through the reaction of reactive esters with carboxylic acids and the combination of amino acids. With low toxicity and high activity, PyBOP is widely used in peptide synthesis, especially for easy-to-racemic amino acids such as histidine. In addition, PyBOP is also a catalyst for synthesizing electrolytes and functional materials, and it has a wide range of applications.

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